If you're organizing a conference, you'll need more than a simple assembly hall or space with a lot of chairs. The hall should be located in a building with an attractive façade and plenty of parking - participants in your conference will only be with you for a day or two, and making a good first impression is vital. You'll most likely need equipment for projecting video and sound (and you may need simultaneous interpreting capabilities). You may also need a separate space for registering participants and coffee breaks.
The key to a successful lecture is isolation from outside noise, whether it's from traffic, a construction site, or neighbouring rooms.